北京市儿童IDDM的发病率调查（1988～1994年）

A survey on the incidence of IDDM in children of Beijing(1988～1994)

为研究北京市儿童可靠的ＩＤＤＭ发病率，于１９９５年对１９８８～１９９４年期间新诊断的０～１４岁的ＩＤＤＭ病例进行了回顾性登记。以全市医院确诊的病例为第－来源，以全市中小学独立调查的病例为第二来源。１９８８～１９９４年北京市０～１４岁的年平均人口为２０７９７４１。医院登记的ＩＤＤＭ患者１３５例，学校调查出４４例，其中４２例与医院相同，总计为１３７例。１９８８～１９９４年平均年粗发病率０．９４／１０万（９５％可信限（ＣＩ）：０．７８～１．１０），确定校正发病率０．９７／１０万（９５％ＣＩ：０．８１～１．１３）。男孩发病率０．７８／１０万（９５％ＣＩ：０．５８～０．９８），女孩发病率１．１１／１０万（９５％ＣＩ：０．８７～１．３６），男女发病率无显著性差异，但是城市发病率（１．０８／１０万）较郊县发病率（０．０６／１０万）显著增高（Ｐ＜０．０５），特别表现在１０～１４岁组，发病率分别为２．１４／１０万和１．１３／１０万（Ｐ＜０．０５）。其原因尚不清楚。

In order to investigate the reliable data on the incidence of insulin dependent diabetes mellitus among children in Beijing,the newly diagnosed cases of IDDM with onset<15 years of age from 1 January 1988 to 31 December 1994 in whole Beijing retrospectively were registered. The first source was based on the medical records from hospitals.The second independent source of information was from all the schools.The average annual population of 0～14 years old was 2 079 741.There were 135 cases were found from hospitals and 44 cases from schools with 42 duplicale,So the total was 137 cases,The average annual crude incidence was 0.94/100000(95%confidence interval(CI):0.78～1.10),and the ascertainment corrected incidence rate was 0;97/100000(95%Q0. 81～1.13).The incidence in boys was 0.78/100000,and 1.11/100000 in girls with no significant difference in sex.But the incidence 1.08/100000 in urban was significantly higher than the incidence 0.06/100000 in rural(P<0.05),especially in 10～14 years age group,the incidence in urban was 2. 14/100000 and 1. 13/100000 in rural(P<0.05).The cause of the difference is not vet clear.