桂皮酰哌啶的合成路线改进

Improved--Synthesis Process Route of Aryl Pyrimidines

通过改变溶剂的方法合成桂皮酰哌啶,以减轻有毒试剂对环境的污染和对人体的伤害。分别选用苯、甲苯、乙酸乙酯、二氯乙烷作为溶剂合成桂皮酰哌啶,结果表明甲苯作为溶剂时产品纯度高,收率高,可用于大规模生产。

The article studied the synthesis process route of aryl pyrimidines by changing solvent,which can reduce the harm to human and the environment. To synthesize aryl pyrimidines by taking benzene,methyl benzene,acetic ether, 1,2-dichloroethane as solvent,the yield and purity of the product are high by taking methyl benzene as solvent. The method is easy and cheap, which it can be used for industry production.