耳穴贴压疗法对阻塞性睡眠呼吸暂停综合征患者睡眠结构的影响及其疗效研究

Clinical Effect of Plaster-Pressure at Ear Point in Obstructive Sleep Apnea Syndrome and Its Influence on Sleep Structure

目的研究耳穴贴压疗法对阻塞性睡眠呼吸暂停综合征(OSAHS)患者睡眠结构的影响,观察其疗效。方法选择OSAHS患者45例,随机分为王不留行药籽贴压耳穴治疗组30例及对照组15例。比较两组患者治疗前、后的临床症状,观察治疗前、后夜间多导睡眠图测定的呼吸暂停指数(AI)、低通气指数(HI)、呼吸紊乱指数(AHI)、最低血氧饱和度(最低SaO2)、最长呼吸暂停时间的变化及Ⅰ期、Ⅱ期睡眠所占时间、所占比例,醒觉次数、醒觉时间等睡眠结构的变化。结果(1)治疗组患者临床症状明显改善,而对照组患者治疗后症状无变化;(2)治疗组患者治疗前、后多导睡眠图(PSG)监测的呼吸参数间差异均有显著性意义(P<0·01)。结论耳穴贴压疗法治疗OSAHS疗效良好。

Objective To investigate the clinical effect and sleep structure changes of patients with obstructive sleep apnea syndrome （OSAHS） treated by plaster -pressure at ear point. Methods Totally 45 OSAHS patients were randomly divided into trial group of piaster -pressure therapy at ear point with Semen Vaccarriae （30 patients） and control group （ 15 Patients）. The changes of clinical symptoms of the patients in the two groups were comparatively analyzed, and apnea index （ AI）, hypo - ventilation index （ HI）, apnea hypopnea index （ AHI）, minimal oxygen saturation of blood （ SaO2 ） and longest apnea time, as well as changes of sleep parameters at night before and after treatment were determined with polysomnography （PSG）. Results After treatment, compared with control group, the clinical symptoms of patients in trial group were obviously improved, and in every parameter in polysomnography there was a significant difference （ P 〈 0. 01 ）. After treatment, the clinical symptoms and every index of patients in the control group were not changed significantly as compared with before treatment. In the trial group, the OSAHS patients showed significant improvement in clinical symptoms and every indexes of PSG （ P 〈0.01 ）. Conclusion The plaster -pressure therapy at ear point has a good effect in treating OSAHS patients. It is a convenient, effective, economical, and side - effect - free method for early prevention and treatment of OSAHS.