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急性高血容量血液稀释并控制性降压在骨科大手术中的应用 被引量:3

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摘要 为探讨急性高容量血液稀释(AHHD)并控制性降压(CH)用于骨科大手术对减少术中出血及对Hb、HCT和凝血功能的影响。将96例骨科大手术病人随机平分为AHHD并CH组(T组)48例和对照组(C组)48例,均采用气管插管全麻。T组于麻醉后切皮前输入6%贺斯20ml·kg^-1,以每分钟50ml输注,并泵入硝普钠控制MAP55—70mmHg,分别于稀释前、后、术毕、术后1天、3天抽血查血常规及凝血功能。并记录术中输血量、输液量、出血量、尿量及术后引流量。结果显示,T组仅有12例病人需要输注浓缩红细胞,而C组38例病人需要输血。T组输血量80±54ml。较C组696nd±112ml明显减少。稀释后,Hb、HCT较稀释前明显下降,凝血功能示APTT、PT延长,PLT、FIB减少(P〈0.05),但却都在正常范围,T组术中出血量明显减少,术后引流量无明显区别。表明AHHD并CH可安全用于骨科大手术,明显减少或避免输注异体血。
机构地区 河南省人民医院
出处 《中医正骨》 2006年第12期17-18,共2页 The Journal of Traditional Chinese Orthopedics and Traumatology
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  • 1Mielke LL,Entholzner EK,Michael K,et al.Preoperative acute hypervolemic hemodilution with hydroxyehtyl starch:an alternative to acute normovolemic hemodilution? Anesth Analg,1997,84(1):26
  • 2Mortelmans Y,Merckx E,van Nerom C,et al.Effect of an equal volume replacenment with 500ml 6% hydroxyethyl starch on blood and plasma volume of healthy volunteers.Eur J Anaesthesiol,1995,12(3):259
  • 3Trouwborst A,van woerkens EC,van Daeie M,et al.Acute hypervolaemic hamodilution to avoid blood transfusion during major surgery,Lancet,1990,336(7):1295
  • 4Ruttmann TG,Jame MFM,Viljoen JF.Haemodilution induces a hypercoagulable.Br J Anaesth,1996,76(3):412
  • 5Lee S H,J Neurosurg,1994年,80卷,469页
  • 6Lo E H,Neurosci Lett,1991年,131卷,17页
  • 7Treib J, HassA, Pindur G, et al.HES200/0.5 is not HES 200/0. 5.Influence of the c2/c6 hydroxyethylation ratio of hydroxyethyl starch(HES) on hemorheology, coagulation and elimination kinetics [ J ]. Thromb Haemost, 1995, 74 ( 6 ) : 1452 -1456.
  • 8London M J, Franks M, Verrier ED, et al. The safety and efficacy of ten percent pentastarch as a cardiopulmonary bypass priming solution . A randomized clinical trial[J]. J Thorac Cardiovasc Surg, 1992,104(2) :284 -296.
  • 9BatHe J, del Rio F, Lopez FM, et al.Effect of dextran on factor Ⅷ/von Willebrand factor structure and function[J]. Thromb Haemost,1985,54(3) :697 - 699.
  • 10Vara - Thorbeck R, Guerrero - Femandez Marcotte JA. Hemodynamicresponse of elderly patients undergoing major surgery under moderate normovolemic hemodilufion[J]. Eur Surg Res, 1985,17(6) : 372-376.

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