空气污染对运动人群血清IL-6、TNF-α表达的影响

A Study on the Effect of Air Pollution on Exercisers' IL-6 and TNF-α in Serum Expression

目的:通过观察血清IL-6、TNF-α含量的变化,探讨大气污染对运动人群免疫功能的影响。方法:在空气污染区选取经常参加户外运动的人群为实验组(EG),非运动人群为阳性对照组(CG1);在洁净区选取健康非运动人群为阴性对照组(CG2)。采用双抗体酶联免疫吸附法(ELISA)测定血清中白介素-6(IL-6)、肿瘤坏死因子(TNF-α)的含量。结果:CG1和EG受试者血清中IL-6、TNF-α含量显著高于CG2(P<0.05,P<0.01);EG血清中TNF-α含量显著高于CG1(P<0.05)。结论:血清中IL-6、TNF-α含量变化与污染物接触量有关。在污染环境中运动更易引起机体的炎性反应,增加对疾病的易感性。

Through observing the changes of IL - 6 and TNF - α, this paper explored the effects of air pollution on immune function in exercisers. Method ： the author Selected 24 workers from heavily polluted area as the experimental group （EG）, with a non - exerciser group as the masculine control group （CG1）, and 12 healthy workers from clean area as the negative control group （CG2）. Using the method of enzyme - linked immunosorbent adsorb （ELISA） to measure the content of interlukin - 6（IL- 6） and tumor necrosis factor- α （TNF - α） . Resuits： The levels of IL- 6 and TNF - α in serum in EG and CG1 are significantly higher than the CG2 （P 〈 0.05, P〈 0.01）. The levels of TNF- α in serum in EG are significantly higher than the CG1 （P〈 0.05）. Conclusions： There is an obvious relationship between the levels of IL- 6 and TNF - α in serum and the contact quantum of air pollutants. Exercising in air polluted environment will induce inflammation reaction and increase the morbid susceptibility for people.