南京市中老年人高尿酸血症检出情况及相关因素的分析

Prevalence and correlated factors of hyperuricemia in the middle-and-old aged inhabitants of Nanjing

目的:了解南京市中老年(45岁以上)人群高尿酸血症的检出情况及相关因素。方法:用随机整群抽样的方法选取社区居民5423人,对其血尿酸、肌酐、胆固醇、三酰甘油、血糖进行测定,并调查其饮食等情况。结果:社区人群中老年人群高尿酸血症患病率为15.0%,男20.1%,女10.6%。男性和女性高尿酸血症患病率在50岁年龄组明显升高,并在以后的年龄组中维持较高水平。高尿酸血症病人血胆固醇、三酰甘油、肌酐、尿酸、血糖、血压、体质指数(BMI)水平均高于非高尿酸血症者。BMI较高(1.512)、患高血压(1.859)为危险因素,而喜热食(0.687)则可能为保护因素。结论:南京市中老年人高尿酸血症以50岁以上为多见。肥胖、患高血压为高尿酸血症的危险因素。

Objective：To learn the prevalence and correlated factors of hyperuricemia in the middleand-old aged inhabitants of Nanjing. Methods：5 423 inhabitants in the districts of Nanjing were selected by random cluster sampling. The levels of uric acid, ereatine, total cholesterol, triglycefides, blood glucose in the serum were measured, and the diet was also investigated. Results ：The prevalence of hyperurieemia in the middle-and-old aged inhabitants was 15.0% , with 20. 1% for males and 10.6% for females. The prevalence for males and females increased after 50 years old, and maintained at a high level afterwards. The concentration of uric acid, creatine, total cholesterol, triglycerides,blood glucose, the blood pressure and BMI in the inhabitants with hyperuricemia were higher than those in the inhabitants without hyperuricemia. The risk factors for hyperuricemia included higher BMI and hypertension, while the protective factor was favorite for hot-food. Conclusion ： For the inhabitants over 45 years old in Nanjing, hyperuricemia was common among the adults over 50 years old. Higher BMI and hypertension were the risk factors, while favorite for hot food was the protective factor.