冠心病患者血清SF、β_2-m和CRP测定的临床意义

Clinical Significance of Determination of Changes of Serum SF,β_2-m and CRP Levels in Patients with Coronary Heart Diseases

目的探讨冠心病患者血清铁蛋白(SF)、β2-微球蛋白(β2-m)和C-反应蛋白(CRP)水平的变化及意义。方法应用放免法和免疫比浊法测定42例冠心病患者血清SF、β2-m和CRP水平的变化,并以35名正常人作对照。结果冠心病患者血清SF、β2-m和CRP水平均非常显著地高于正常人组(P<0.01),且SF、β2-m和CRP水平呈明显正相关(r=0.6285、0.6018,P<0.01)。结论检测冠心病患者血清SF、β2-m和CRP水平的变化对了解病情、指导临床实践均具有重要的临床价值。

Objective To investigate the clinical significance of changes of serum SF, β2-m and CRP levels in patients with comary heart diseases. Methods Serum SF, β2-m levels were detected with RIA and CRP levels with immuno turbidity in 42 cases of coronary heart diseases and 35 controls. Results The levels of serum SF, 62 - m and CRP were significantly higher in the patients than those in coatrols （ P 〈 0.01 ）. Serum SF, β2- m and CRP levels were mutually positively correlated （ r = 0. 6285,0. 6018,P 〈 0. 01 ）. Conclusion Serum SF, β2-m and CRP levels were closely related to the diseases process of coronary heart diseases and were of prognostic values.