小儿非典型肺炎患者肺炎支原体感染状况分析

Incidence of Mycoplasma Infection in Child Atypical Pneumonia

目的了解2004年1月～2005年12月我院小儿非典型肺炎患者肺炎支原体(Mycoplasmapneumon-iae,MP)感染状况。方法采用日本赛乐迪亚-麦可Ⅱ肺炎支原体抗体诊断试剂盒,以被动凝集法检测社区获得性肺炎患儿血清中肺炎支原体抗体。结果2004年度我院共检测小儿非典型肺炎患者血清460例,其中阳性97例,阴性363例,由肺炎支原体感染引起的非典型肺炎发病率为21.1%。2005年度共检测小儿非典型肺炎患者血清850例,其中阳性255例,阴性595例,由肺炎支原体感染引起的非典型肺炎发病率为30·0%。根据第四军医大学统计教研室编写的SLPM3.0统计软件计算得2005年由肺炎支原体感染引发的小儿非典型肺炎发病率较2004年有显著性升高(χ2=12.0668,P<0.01)。不同月份肺炎支原体感染引发的小儿非典型肺炎发病率无显著性差别(2004年χ2=8.5267,P>0.05,2005年χ2=2.5031,P>0.05)。结论肺炎支原体感染是引起我院2005年小儿非典型肺炎的重要原因;2005年是我院所在地区支原体肺炎感染高峰年。

Objective To study the incidence of mycoplasma infection in child atypical pneumonia patients admitted to this hospital from Jan. 2004 through Dec. 2005. Methods Serum myeoplasm pneumonia antibody was detected with passive agglutination method （ using Japanese made reagents） in all the children with atypical pneumonia encountered in 2004 and 2005 （ n = 1310）. Results In 2004, 97 of the 460 speciments were positive for mycoplasma antibody （21.1% ）. In 2005, the positive rate increased significantly to 30.0% （255/850） （P 〈 0.01 ）. However, the monthly difference of the incidence was overall not significant. Conclusion In Jinan area, 2005 was a year with high incidence of mycoplasmic atypical pneumonia in ehildern.