影响包头市献血员丙氨酸氨基转移酶测定结果因素的分析

The Influence Factor on ALT Test for Donated Blood in Baotou City

目的本研究通过对4600例献血者检测，对几个因素的对照分析，确定引起丙氨酸氨基转移酶（ALT）不合格的高危因素，从而决定献血前健康咨询筛检策略，根据不同人群选择不同的采血模式及对检测后检测结果进行科学的解释工作。方法选择连续监测法原理的酶标板速率法对献血者新鲜血浆进行ALT测定。结果包头市献血员男性的95％可信区间小于54．93IU／L，女性小于38．48IU／L；男性ALT不合格率（19．5％）高于女性（5．0％）；体重大于75k的人群ALT不合格率（29．2％）高于45～75kg人群（10．4％）；军人及大专院校学生ALT不合格率低（分别为2．6％和1．6％）；31～43岁年龄段不合格率（17．5％）高于18～30岁年龄段（12．8％）及44—55岁年龄段（15．7％）；不同民族的ALT不合格率差异无统计学意义；包头市周边旗县区的ALT不合格率高于市区。结论不同人群ALT活性不同，应采取不同的献血前宣传咨询策略；采用不同的采血模式：正常体重的大专院校学生、军人、妇女适合针对ALT的非预检采血，高体重、男性、包头周边旗县区人群适合针对ALT的预检后当日采血模式。

Objective To make an estimate of the 95% area of serum ALT levels in Baotou blood donors; and to assess the main relationship to the elevated alanine aminotransferase （ALT） in blood donors; and to seek medical advice before donating blood. Choose a work model suitable for donors. Methods Test serum alanine aminotransferase （ALT） in blood donors with continue test methods. Results The95% area of serum ALT levels in Baotou blood donors ： male was 54. 93 IU/L, female was 38.48 IU/L; male＇ s ALT values was higher than female＇ s ; the rate of positive of students and servicemen was the most lowest; rate of positive of 31 - 43 age is the most highest; the rate of positive of weight above 75 kg was higher than that the weigh blow 76 kg; the rate of positive of the municipal district people was lower than the county people. Conclusion Student, serviceman, woman, and right weight people can donate blood without laboratory examination, fat man, drink hard people and county people donate blood after laboratory examination intead.