结直肠颗粒细胞瘤

Granular cell tumor of colon and rectum

颗粒细胞瘤起源于雪旺细胞。结直肠颗粒细胞瘤发生率在消化道中仅次于食道。大多结直肠颗粒细胞瘤无临床症状,术前明确诊断比较困难,内镜下治疗是良性结直肠颗粒细胞瘤的首选治疗方法。恶性结直肠颗粒需要行局部广泛切除,必要时加上区域淋巴结清扫,预后较差。

Granular cell tumor （GCT） is of schwann cell origin. GCT of the colon and rectum is an uncommon mesenr chymal lesion. In the gastrointestinal tract, the colon and rectum follows the esophagus in terms of the frequency of occurrence of these tumors. GCT is often an incidental finding on a colorectal examination for other underlying diseases. The digonosis of this tumor is dificullt. As to therapy, benign GCT of the gastrointestinal tract can best be removed endoscopically. Wide local excision with regional lymph node dissection remains the mainstay of treatment of malignant GCT, but receive a bad prognosis.