摘要
目的 观察膳食疗法是否可减轻反应停治疗多发性骨髓瘤的副反应。方法 将64例应用反应停联合VAD方案化疗的多发性骨髓瘤患者随机分为观察组与对照组，每组32例；对照组采用常规护理方法，观察组加用膳食疗法，比较两组的疗效和副反应发生率。结果 观察组的副反应发生率明显低于对照组（P〈0．05～0．01），但两组疗效的差异无统计学意义（P〉0．05）。结论 膳食疗法可明显减轻反应停治疗多发性骨髓瘤的副反应。
Objective To observe whether diet therapy can alleviate thalidomide- induced side effects in multiple myeloma （MM）. Methods Sixty- four patients with MM underwent thalidomide plus VAD chemotherapy were randomly divided into 2 groups： control group （ n = 32） received conventional nursing, and treatment group （n=32） accepted diet therapy. The therapeutic efficacy and incidence of side effects in both groups were compared. Results The incidence of side effects was significantly lower in treatment group than that in control group （P 〈 0.05 -0. 001 ）, but there was no statist tical difference in the therapeutic efficacy between both groups （P 〉0.05）. Conclusion Diet therapy may decrease the side effects induced by thalidomide in patients with MM.
