钠曲线与超滤曲线结合对血液透析低血压的防治作用

Efficacy of sodium profile combined with ultrafiltration profile on preventing intradialytic hypotension

目的探讨钠曲线(Sodium Profile,SP)与超滤曲线(Ultrafiltration Profile,UP)联合应用对血液透析低血压的防治作用。方法对10例维持性血液透析患者进行普通透析(CHD)及SP+UP透析各10次,监测透析过程中血压及血容量变化。结果CHD和SP+UP发生低血压的例次分别为22次和8次(2χ=7.063,P=0.008);透析结束时,CHD和SP+UP血容量分别下降(15.46±5.52)%和(9.21±5.23)%(P<0.05)。结论SP+UP对血容量有较好的维持作用,能显著降低透析低血压的发生。

Objective To investigate the efficacy of sodium profile（SP） combined with ultrafiltration profile（UP） on preventing from the intradialytic hypotension. Methods Ten stable hemodialysis patients underwent common hemodialysis（CHD） and SP＋ UP hemodialysis for 10 times, respectively. The blood pressure and the variation on blood volume were measured. Results The frequency of hypotension was 22 times in CHD,and 8 times in SP＋UP （X^2 = 7. 063,P = 0. 008）. At the end of the hemodialysis, the decrease of blood volume was（15. 46±5. 52）% in CHD, and（9. 21 ±5. 23）% in SP＋UP （P 〈 0.05）. Conclusions The blood volume is better preserved and the intradialytic hypotensive episodes decrease significantly in SP＋ UP.