精神分裂症患者乙型肝炎病毒感染调查

Survey of hapatitis B virus infection in schizophrenic patients

目的:调查精神分裂症患者的乙型肝炎病毒(HBV)感染与肝功能异常情况。方法:对312例精神分裂症住院患者的HBV感染及丙氨酸氨基转移酶(ALT)异常进行流行病学调查,以健康体检者279名为对照。结果:精神分裂症患者的HBV感染率为71.8%,ALT异常率为29.5%,明显高于对照组,精神分裂症患者中两性间HBsAg阳性率以男性显著较高。再次住院患者的HBV感染显著比首次住院患者高。结论:对精神分裂症患者应加强隔离措施,特别是HBsAg阳性的患者,防止交叉感染;加强健康教育,加强饮食营养支持和乙肝疫苗的接种等措施。

Objective： To survey the hapatitis B virus （HBV） infection and liver function condition in schizophrenic patients Method：312 schizophrenic patients and 279 healthy controls were, surveyed in HBV infection were tested of serum alamine aminotransferase （ALT）, Results： The rate of HBV infection in schizophrenic patients was 71.8% and ALT abnormality rate was 29.5%. It was significandy higher than the control group. HBV infection rate of the repeat admitted inpatients were higher than the first admitted inpatients. Conclusion： Strengthen the insulation measure towards inpatients of schizophrenia, prevent form the dissemination, strengthen the education about health, and notice the food nourishment support and B liver vaccines include.