摘要
目的:优选康复新滴丸的最佳工艺条件。方法:以滴丸的外观质量、丸重变异系数、崩解时限为指标,采用正交实验设计。结果:最佳工艺条件为PEG6000:药物为4∶1,料液温度75°C,滴速40滴/m in。结论:正交试验确定的最佳工艺条件合理可靠,重现性良好。
AIM： To selecte the best process for Kangfuxin Drop Pills. METHODS： With appearance, weight coefficient of variation and dissolution time for index sign, orthogonal design was applied. RESULTS： The results indicated that the excellent factors and levels were as follows： the scale between PEG6000 and drug extraction was four to one, the temperature of drug fluid was at 85 ℃, drip rate was 40 drops/mitt. CONCLUSION： The method adopted is steady and feasible.
出处
《中成药》
CAS
CSCD
北大核心
2006年第12期1728-1731,共4页
Chinese Traditional Patent Medicine
关键词
康复新滴丸
成型工艺
正交实验
Kangfuxin Drop Pill
formulation process
orthogonal design
