摘要
目的:优选康复新滴丸的最佳工艺条件。方法:以滴丸的外观质量、丸重变异系数、崩解时限为指标,采用正交实验设计。结果:最佳工艺条件为PEG6000:药物为4∶1,料液温度75°C,滴速40滴/m in。结论:正交试验确定的最佳工艺条件合理可靠,重现性良好。
AIM: To selecte the best process for Kangfuxin Drop Pills. METHODS: With appearance, weight coefficient of variation and dissolution time for index sign, orthogonal design was applied. RESULTS: The results indicated that the excellent factors and levels were as follows: the scale between PEG6000 and drug extraction was four to one, the temperature of drug fluid was at 85 ℃, drip rate was 40 drops/mitt. CONCLUSION: The method adopted is steady and feasible.
出处
《中成药》
CAS
CSCD
北大核心
2006年第12期1728-1731,共4页
Chinese Traditional Patent Medicine
关键词
康复新滴丸
成型工艺
正交实验
Kangfuxin Drop Pill
formulation process
orthogonal design