1Abou-Zeid C,Gares MP,Inwald J,et al.Induction of a type 1immune response to a recombinant antigen from Mycobacterium tuberculosis expressed in Mycobacterium vaccae[J].Infect Immun,1997,65:1856-1862.
2Reyrat JM,Lopez-Ramirez G,Ofredo C,et al.Urease activity does not contribute dramatically to persistence of Mycobacterium bovis bacillus Calmette-Guerin[J].Infect Immun,1996,64:3934 -3936.
3Rao V,Dhar N,Tyagi AK.Modulation of host immune responses by overexpression of immunodominant antigens of Mycobacterium tuberculosis in bacille Calmette-Guerin[J].Scand J Immunol,2003,58:449-461.
4Horwitz MA,Harth G.A new vaccine against tuberculosis affords greater survival after challenge than the current vaccine in the guinea pig model of pulmonary tuberculosis[J].Infect Immun,2003,71:1672-1679.
5Zheng C,Xie P,Chen Y.Recombinant Mycobacterium bovis BCG producing the circumsporozoite protein of Plasmodium falciparum FCC-1/HN strain induces strong immune responses in BALB/c mice[J].Parasitol Int,2002,51:1-7.
6Nascimento IP,Dias WO,Mazzantini RP,et al.Recombinant Mycobacterium bovis BCG expressing pertussis toxin subunit S1 induces protection against an intracerebral challenge with live Bordetella pertussis in mice[J].Infect Immun,2000,68:4877-4883.
7Young S,O'Donnell M,Lockhart E,et al.Manipulation of immune responses to Mycobacterium bovis by vaccination with IL-2-and IL-18-secreting recombinant bacillus Calmette Guerin[J].Immunol Cell Biol,2002,80:209-215.
8Gheorghiu M,Lagrange PH,Fillastre C.The stability and immunogenicity of a dispersed-grown freeze-dried Pasteur BCG vaccine[J].J Biol Stand,1988,16:15-26.
9Dietrich G,Mollenkopf HJ,Weber H,et al.Cultivation of Mycobacterium bovis BCG in bioreactors[J].J Biotechnol,2002,96:259-270.
10Fotinou C,Emsley P,Black I,et al.The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin[J].J Biol Chem,2001,276:32274-32281.