超临界萃取女贞子中齐墩果酸的实验研究

Experiment Research on OA of SFE from Fructus Ligustri Lucidi

以齐墩果酸作为考察指标,分别考察了夹带剂种类、萃取压力、温度、萃取时间、二氧化碳流量、物料粒度、夹带剂用量、乙醇浓度、预处理等单因素对萃取结果的影响,采用正交实验设计方法,以浸膏收率、齐墩果酸的含量为指标,优化女贞子的超临界CO2萃取工艺,优化条件为:以与物料质量比为1∶1(v/w)的80%乙醇浸润物料1h后萃取,压力18MPa,温度60℃,以与物料比为2∶1(v/w)的95%乙醇为夹带剂,CO2流量为4.8L/h,萃取时间为3h.

Taking OA as standard, the effects of kinds of entrainer, pressure, temperature, time, the flow rate of C/32, matrix granularity, volume of entrainer, concentration of ethanol and pretreatment to the extractive results of Fructus ligustri lucidi were studied, at the same time, the curves of the influence factors were drawn. The optimum conditions for SFE- CO2 was selected with the aid of orthogonal design by using the content of OA as criteria. The results were as followed：soak the matrix by 80% ethanol （contrast to matrix 1 ： 1 v/w） for an hour, pressure 18Mpa, temperature 60℃, the flow rate of CO2 4.8L/h,95% ethanolas entrainer （contrast to matrix 2：1 v/w）and extraction time 3h.