期刊文献+

前列腺素E1治疗糖尿病肾病临床疗效观察 被引量:2

下载PDF
导出
摘要 治疗组24例予前列腺素E1,10ug/d,静脉注射连续14d。观察两组治疗前后及组间相关指标的变化,3个月后随访。结果:治疗组3组患者24小时尿白蛋白排泄率和尿β2-微球蛋白较治疗前有明显下降(P<0·05),且与对照组治疗后相比较均有显著性差异(P<0·05)。治疗后3个月随访显示,治疗组3组尿蛋白水平无明显变化。结论:短期静脉应用前列腺素E1治疗糖尿病肾病,对不同时期患者均有减少尿蛋白作用,随访3月尿蛋白无明显回升。
出处 《实用糖尿病杂志》 2006年第6期51-52,共2页 Journal of Practical Diabetology
  • 相关文献

参考文献3

  • 1S. Yamamura K, Matsushita M, et al. lontophoretic application of prostaglandin E, for improvement in peripheral microcirculation. Int J Clin Pharmacol Ther 1998,6:529.
  • 2Okada S, Iehiki K, Tanukuchi S, et al. Effect of Prostaglaudin E1 on the rennin - oldlstrlone system in patients with diabetic nephropathyg. Int Med Res 1993,21(2):126 - 132.
  • 3卢爱华,胡敏.前列腺素E_1在糖尿病慢性并发症中的应用研究[J].国外医学(内分泌学分册),2000,20(3):135-137. 被引量:110

二级参考文献10

  • 1Cawello W,Leonhardt A,Schweer H,etal.Dose proportional pharmacokinetics of alpro-stadil (prostaglandin E1)in healthyvolunteers following intravenous infusion 〔J〕.Br J Clin Pharmacol,1995,40:273~276.
  • 2Anggard E.The biological activities of three metabolites of prostaglandin E1 〔J〕.ActaPhysiol Scand,1996,66:509~510.
  • 3Yasuda H,Maeda K,Sonobe M,et al.Metabolic effect of PGE1 analogue O1206.αCD onnerve Na+-K+-ATPase activity of rats with streptozotocin-induced diabetes is mediatedvia cAMP: possible role of cAMP in diabetic neuropathy 〔J〕.Prostaglandins,1994,47:367~378.
  • 4Okada S,Ichiki K,Tanokuchi S,et al.Effect of prostaglandin E1 on therenin-aldosterone system in patients with diabetic nephropathy 〔J〕.J Int MedRes,1993,21:126~132.
  • 5Young MJ, Veves A,Smith JV, et al.Restoring lower limb blood flow improvesconduction velocity in diabetic patients 〔J〕.Diabetologia,1995,38:1051~1054.
  • 6Partanen J,Niskanen L,Lehtinen J,et al.Natural history of peripheral neuropathy inpatients with non-insulin-dependent diabetes mellitus 〔J〕. N Engl J Med,1995,333:89~94.
  • 7Yasuda H,Sonobe M,Hatanaka I,et al.A new prostaglandin E1 analogue (TFC-612)prevents a decrease in motor conduction velocity in streptozocin-diabetic rats 〔J〕.BiochemBiophys Res Commun,1998,150:225~230.
  • 8Shindo H,Tawata M,Inoue M,et al.The effect of prostaglandin E1.αCD on vibratorythreshold determined with the SMV-5 vibrometer in patients with diabetic neuropathy 〔J〕.DiabetesRes Clin Pract,1994,24:173~180.
  • 9Okada S,Sato K,Higuchi T,et al.Influence of prostaglandin E1 on slight proteinuriain non-azotaemic diabetes 〔J〕.J Int Med Res,1992,20:94~97.
  • 10Creutzig A,Bullinger M,Cachovan M,et al.Improvement in the quality of life afteri.v.PGE1 therapy for intermittent claudication 〔J〕.Vasa,1997,26:122~127.

共引文献109

同被引文献7

引证文献2

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部