急性心肌梗死急诊溶栓的临床观察

A clinical observation of emergency thrombolytic therapy for patients with acute myocardial infarction

目的探讨急性心肌梗死(AMI)急诊溶栓的疗效和安全性。方法60例AMI患者被随机分为急诊溶栓组(A组)和入院后溶栓组(B组),各30例。A组患者诊断为AMI后,在急诊科立即给予尿激酶(UK)静脉点滴,B组患者按常规办完入院手续后再按上述方法溶栓治疗。结果从发病到开始溶栓的时间: A组(145±33)min,B组(253±116)min(P<0．05)。梗死相关血管开通率:A组86．7％,B组63．3％(P< 0．05)。A、B两组的并发症发生率相似。结论急诊溶栓可缩短AMI患者溶栓开始的时间,增加冠状动脉的再通率,安全可行。

Objective To study clinical effect and safety of intravenous thrombolytic emergency treatment for patients with acute myocardial infarction（AMl）. Methods 60 patients with AMI were randomly divided into two groups ： emergency thrombolysis group（A group, n = 30 ） and inhospital thrombolysis group （ B group, n = 30 ）. The patients in group A were immediately given urokinase（UK） by intravenous drip in emergency department. The patients in group B were given UK by intravenous drip after admission to the hospital. Results In group A and group B, the time from AM I onset to initiation of thrombolysis was respectivcly（ 145 ± 33 ）min and （253 ± 116）min （P〈0.05）;The vessel reperfusion rates of infarct-related artery was 86.7% .63.3% （P〈0.05）.Conclusion Emergency thrombolytic therapy may safcly shorten the time from AMI onset to initiation of thrombolysis and increase coronary artery recanalization rate.