OCT3000与HRT-Ⅱ在青光眼检查中的诊断评估

Diagnostic assessment of OCT3000 and HRT-Ⅱ in detecting glaucoma

目的比较OCT3000与HRT-Ⅱ对正常眼和开角型青光眼的诊断能力。方法对54例86眼(正常46眼,开角型青光眼40眼)OCT3000、HRT-Ⅱ检测的各项参数行受试者特征曲线(ROC)分析,评价不同参数对于青光眼的诊断价值。对两种检查方法进行一致性评估。结果最佳敏感性、特异性和ROC曲线下面积是OCT3000(下方神经纤维层厚度90,89.1,0.936),HRT-Ⅱ(盘沿面积82.5,87,0.919)。OCT3000和HRT-Ⅱ之间的结果判断一致性(kappa值)是0.661。结论两种仪器检测青光眼时具有良好的一致性。OCT3000较HRT-Ⅱ拥有更好的诊断价值。

Objective Measurement of the optic nerve head（ONH） and retinal nerve fiber layer（RNFL） can offer the valuable parameters for the early diagnosis and monitor of glaucoma. Mueh equipment have been utilized to measure and calculate these data. We compared the effect of Heidelberg retina tomograph-Ⅱ （ HRT-Ⅱ ） and optical coherence tomography 3000 （OCT3000） to differentiate healthy eyes and glaucomatous eyes. Methods Forty eyes with upen-angle glaueomatous eyes were examined using HRT- Ⅱ and OCT3000, and 46 normal eyes from age-matched subjects were as control. The receiver operating characteristic curves （ROC） of examinees were calculated. Each parameter including ONH, RNFI, thickness from HRT- Ⅱ and OCT3000 measurements was compared, and the diagnostic value of different parameter was evaluated. Results Optimal sensitivities,speeifieities,and areas under ROC were 82.5,87,0.919 in rim area in HRT-Ⅱ ; the inferior RNFL thickness was 90,89. 1,0. 936 in OCT3000. Agreement on categorization （ the kappa value） between HRT- Ⅱ and OCT3000 was 0. 661. Conclusion Agreement on categorization between OCT3000 and HRT-Ⅱ in detecting glaucoma is substantial. According to the assessment of all parameters from these two instruments,OCT3000 has a better diagnostie value than HRT-Ⅱ.