摘要
丙戊酸钠(VAP)诱发癫痫患儿体质量增加的原因较多,许多研究发现瘦素是其主要原因。本文从瘦素降低、瘦素抵抗、瘦素与胰岛素的双向作用这三个方面,综述了近年来国内外有关VAP诱发癫痫患儿体质量增加与瘦素影响的研究进展。
Weight gain resuhing from valproate in childhood has many factors, in which leptin is a main reason. This article reviews research progress of valproate about its weight gain and its influence on leptin from leptin decrease, leptin resistance and bilateral effects between leptin and insuline.
出处
《医学综述》
2006年第24期1526-1527,共2页
Medical Recapitulate