摘要
目的观察阿托伐他汀强化治疗对急性冠脉综合征（ACS）的作用。方法选择61例ACS患者，随机分为两组。治疗组31例，给予阿托伐他汀钙30—40mg／d口服；对照组30例，给予阿托伐他汀钙10mg／d口服，疗程均为3个月。观察两组患者的临床疗效覆治疗前、后血脂改变情况。结果两组忠者治疗前、后低密度脂蛋白胆固醇（LDL—C）、三酰甘油（TG）、总胆固醇（TC）明显下降，差异有显著性意义（P〈0．01）；治疗组治疗后LDL—C、TG、TC较对照组下降明显（P〈0．05），临床症状改善间差异亦有显著性意义（P〈0．05）。结论阿托伐他汀强化治疗效果良好，30～40mg／d是安全的，他汀类药物对防治冠心病有重要意义。
Objective To observe the effect of Atorvastatin intensive treatment towards ACS. Methods All 61 ACS patients choosing in random were divided into two groups. Intensive treatment group （31 cases） chooses Atorvastatin made in Huirui Company. It is taken orally 30 -40mg/d. The common treatment group （30 cases ） is taken orally 30 -40mg/d, The course of treatment is three months. Results Compared with the past the LDL - C,TG, TC in these two groups fall Obviously （ P 〈0, 01）. Compared with the past the LDL-C, TG, TC in the intensive treatment group fall Obviously （ P 〈0. 05）. The abnormity in clinical symptom alleviatition is also significant （ P 〈 0. 05 ）. Conclusion Atorvastatin Intensive treatment can raise ACS patients＇. The quantity 10-40mg/d is safe. It has significant meaning for tatin drug in the provention and cure of ACS.
出处
《实用心脑肺血管病杂志》
2006年第10期801-802,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
