摘要
过氧化损伤是导致精子质量下降的重要原因之一,辅酶Q10是一种存在于线粒体中的脂溶性抗氧化剂,其在精浆和精子中的水平对男性生殖系统的抗氧化损伤能力具有重要影响。外源性补充辅酶Q10有利于改善精子质量,提高不育患者生育能力,对男性不育具有一定的辅助治疗作用。现就辅酶Q10的生物学功能及其对精子质量的影响,以及对男性不育的辅助治疗作用等方面作一综述。
Oxidative damage is one of the important factors inducing the degression of sperm quality. CoQ10 is a liposoluble antioxidant that exists in mitochondria and its levels in semen and spermatozoa have an important role in the oxidation resistance of the male genital system. Exogenous administration of CoQ10 can improve the sperm quality and reproductive ability of infertile patients as well as exert the effects of an adjunctive therapy on male infertility. This review describes the biological function of CoQ10 and its effect on the quality of spermatozoa and its effect as an adjunctive therapy on male infertility.
出处
《中华男科学杂志》
CAS
CSCD
2006年第12期1119-1122,共4页
National Journal of Andrology
关键词
辅酶Q10
精液
精子质量
男性不育
coenzyme Q10
semen fluid
sperm quality
male infertility
