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间充质干细胞对自然杀伤细胞分泌γ-干扰素的影响

The Inhibitory Effect of MSC on IFN-γ Secretion of Purified NK Cells
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摘要 目的:研究间充质干细胞(MSC)是否能够抑制NK细胞产生γ-干扰素(IFN-γ)。方法:应用酶联免疫吸附试验测定MSC上清中IFN-γ的分泌水平。结果:有MSC上清减少NK细胞分泌IFN-γ的水平。结论:MSC可抑制NK细胞分泌IFN-γ。 Objective ： To study if MSC can inhibit IFN -γ secretion from purified NK cells. Methods ： The level of IFN - γ in the serum of MSC was determined by enzyme linked immunosorbant assay（ELISA）. Results ：MSC could lower the level of IFN -γ secreted by activated NK cells; conclusion ： MSC can inhibit IFN - γ secretion from purified NK cells.
作者 张涛 张丽华 许艳红 刘荣
机构地区 包头医学院基础部病原生物教研室
出处 《包头医学院学报》 CAS 2006年第4期365-367,共3页 Journal of Baotou Medical College
关键词 间充质干细胞 自然杀伤细胞 Γ-干扰素 免疫抑制 Mesenchymal stem cells Natural killer （NK） ceils IFN -γ Immune suppression
分类号 R392.1 [医药卫生—免疫学]
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参考文献13

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共引文献21

包头医学院学报
2006年 第4期

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