胃癌淋巴结转移的模糊数学研究

Study on the Lymphatic Metastasis of Gastric Cancer by Fuzzy Mathematics

作者采用模糊数学方法研究了１１４例胃癌组织学表现与胃周淋巴结转移的关系。结果表明：胃癌浸润深度、生长方式、异型性、淋巴管和血管侵犯程度、癌间质淋巴细胞浸润程度、间质胶原纤维反应程度与淋巴结转移密切相关。用以上指标计算出判别值（２．９９９）进行判断，有淋巴结转移的符合率为８０．６％，无淋巴结转移的符合率为６１．９％。作者认为该方法在判断胃癌淋巴结转移方面，尤其对隐性转移和缺乏淋巴结材料的病例具有一定的参考意义。

The relationship between the histologic features of 114 cases with gastric carcinoma and perigastric lymphatic metastasis was investigated by means of fuzzy mathematics.The results showed that among the pathohistologic features of gastric carcinoma,the depth of invasion, the way of growth, atypia, invasion of lymphatic and blood vessels, infiltration of the lymphocytes in cancerous stroma and reaction of collagen were obviously contributive to the lymphatic metastasis. Ascertaining the metastasis with the distinguishing value(2.999)calculated by means of above indexes,80.6% of metastasis in theory accorded with the pathological diagnosis, and 61.9% in nonmetastastic cases.It is suggested that this method is beneficial in determining the lymphatic metastasis of gastric carcinoma,especially for the latent metastasis and the cases lacking pathological data of lymph nodes.