急性有机磷农药中毒患者肌钙蛋白-I的变化

The Variation of Cardiac Troponin-I in Patients with Acute Organophosphorous Pesticide Poisoning

目的:探讨急性有机磷农药中毒患者心肌肌钙蛋白-I(cTn-I)的变化。方法:利用化学发光免疫测定法对114例急性有机磷中毒患者cTn-I水平进行测定,并观察患者心脏功能的改变。结果:急性有机磷中毒患者cTn-I水平均有不同程度升高,其升高与中毒程度呈正相关,并随病情缓解呈恢复趋势。结论:急性有机磷中毒患者的病情与cTn-I浓度的变化密切相关,监测急性有机磷农药中毒患者cTn-I的水平有重要的临床意义。

Objective： To explore the variation of cardiac troponin Ⅰ （cTn-Ⅰ） in patients with acute organophosphoro＇us pesticide poisoning. Methods： The cTn-Ⅰ level in 114 patients with acute organophosphorous pesticide poisonlngwas tested using chemiluminescent immunoassay（CLIA）, and the variations of heart function in these patients was observed. Results; The level of cTn-Ⅰ in all patients increased in varying degrees. There was a positive correlation between the increase of cTn-Ⅰ and the degree of poisoning, and the level of cTn-Ⅰ decreased along with the recovery of illness. Coliciusion; the level of cTn-Ⅰ in patients with acute organophosphorous pesticide poisoning has a close relationship to the pathogenetic condition, It is of importance clinical significance to monitor the level of cTn-Ⅰ in patients with acute organophosphorous pesticide poisoning.