后部缺血性视神经病变临床观察

Clinical observation of posterior ischemic optic neuropathy

目的:通过回顾性研究,探讨后部缺血性视神经病变(pos-teriorischemicopticneuropathy,PION)的临床表现、发病机制、诊断及治疗预后。方法:对9例(12眼)PION患者常规行眼部检查及全身检查,并排除压迫性、炎性、青光眼性或其它视神经疾病。行中医综合治疗。观察视力、视野、眼前节及眼底体征。结果:9例12眼均有不同程度视力下降及视野缺损;眼底视盘及视网膜正常6眼,视盘变淡或苍白6眼。经治疗的8例10眼,有效率70%。结论:PION是一种独立的临床眼病,诊断强调排除其它视神经疾病或眼病,中医综合治疗有助于视力改善。

AIM： To study the clinic features, pathogenesis, diagnosis and treatment of posterior ischemic optic neuropathy （PION） through retrospectively observation. METHODS： Nine patients （12 eyes） with PION underwent routine ophthalmologic and systemic examinations, as well as integrated treatment by Chinese medicine. Main outcome measures included visual acuity （VA）, visual field, signs of the anterior segment and fundus. Compressive, inflammatoryr glaucomatous or other optic nerve disorders were excluded, RESULTS： All patients had visual loss and visual field defects. Six eyes had normal optic disc and retina, and the disc became atrophic in 6 eyes. Ten eyes of 8 cases had been treated, and 70% experienced improvement in vision.CONCLUSION： PION is a distinct clinical entity, but should be diagnosed only after exclusion of all other causes of visual loss. Integrated therapies of Chinese medicine were helpful for the improvement in vision.