经济发达地区社区人群代谢综合征患病率及其主要临床症候的多样性

The Prevalence of Metabolic Syndrome and Its Clinic Polymorphism of Main Signs among Community Population in Economy Developed Regions

目的了解经济发达地区城市和农村社区人群代谢综合征(m etabolic syndrom e,MS)的流行病学及临床特征。方法利用中国心血管健康多中心合作的研究资料,对苏州市和常熟市2个社区35岁以上人群MS的分布和临床症候群聚集特点进行了分析。结果城市社区MS患病率(30.5%)高于农村社区(18.1%),男性和女性的患病率分别为19.3%和28.0%,MS患病率均随年龄增加而增高。MS 5项诊断指标中,腰围(WC)、三酰甘油(TG)和高密度脂蛋白(HDL-C)异常的百分率均在80%以上;此外,高血压占71.1%,高血糖(GLU)仅占35.8%。MS患者中,包括全部5项诊断指标者占10.3%,4项者占30.2%,3项者占59.5%。MS的诸症候中,WC、TG、HDL-C异常和WC、TG、HDL-C异常、高血压合并的比例最高;5项指标聚集以及TG、HDL-C异常、高血压和WC、HDL-C异常、高血压也分别各占10%;但HDL-C、GLU异常、高血压;TG、HDL-C、GLU异常、高血压;TG、GLU异常、高血压;WC、TG、GLU异常;WC、HDL-C、GLU异常形成症候聚集的比例却很低。结论经济发达地区城市和农村社区MS患病率已达到了比较高的水平;在MS诸症候中,具有WC就非常容易形成危险因素的聚集;临床多样性的分析提示,WC、TG、HDL-C似乎构成了MS的核心症候群。

Objective To explore the main epidemiological characters of metabolic syndrome among urban and rural community population in economy developed regions. Methods Based on the data of two community population from Chinese Muhicenter Cardiovascular Health Cooperative Project, the distribution characters of metabolic syndrome and its Clinic polymorphism of aggregation of main signs were analysed. Results The prevalence of metabolic syndrome among urban community population was higher than rural community population（30.5% ：18.1% ） ; The prevalence among the male was lower than the female（ 19.3% ：28.0% ） ; The prevalence was rising with age. Among the five diagnostic standards, WC, TG and HDL-C all accounted for more than 80% ; hypertension accounted for 71.1% ; GLU accounted for 35.8%. Among the patients with metabolic syndrome, who had all of the five diagnostic standards accounted for 10. 3% , who had four diagnostic standards accounted for 30. 2% , who had three diagnostic standards accounted for 59.5%. Among the signs of metabolic syndrome, the aggregative proportion of WC, TG, HDL-C and WC, TG, HDL-C, hypertension was higher, the aggregative proportion of HDL-C, GLU, hypertension; TG,HDL-C, GLU, hypertension; TG, GLU, hypertension; WC, TG, GLU; WC, HDL-C, GLU was lower. Conclusion The prevalence of metabolic syndrome among urban and rural community population in economy developed regions had reached higher level. Among the signs of metabolic syndrome, if WC existed, it was easier to aggregate for other risk factors. The analysis of clinic polymorphism suggested, WC, TG and HDL-C seemed to constitute the core signs of metabolic syndrome.