摘要
目的研究康脉3号胶囊在治疗糖尿病足中的作用和机理。方法以康脉3号胶囊为治疗组(20例),以通塞脉片为对照组(20例),观察治疗前后患者的症状、体征、血脂、血液流变学及血液中内皮素(ET)、血栓素B2(TXB2)、一氧化氮(NO)、6-酮-前列腺素F1α(6-K-PGF1α)及血浆内皮活性因子的变化情况。结果康脉3号胶囊能够明显降低糖尿病足患者血浆ET、TXB2水平,而升高NO、6-K-PGF1α,优于对照组。结论康脉3号胶囊能抑制糖尿病足的发生发展。
Objective To study the effect and mechanism of Kangmai （康脉） 3 capsule in treating diabetic food Methods Twenty patients with DF were treated by Kangmai 3 capsule as the therapeutic group and another 20 patients treated by Tongsaimai （通塞脉） tablet as the control group. Changes of the patients＇ symptoms and physical signs before and after treatment were observed, and the criteria of blood-fat, hemodynamics, blood endothelin （ET）, thromboxane B （TXB2） 6-ketopredtaglandin F1 （6-K-PGF1） and plasma endotheliocytic active factor were determined. Results In the Kangmai 3 capsule group, levels of plsama ET, TXB2 decreased while those of NO, 6-K-PGF1 increased more markedly than in the control. Conlusion Kangmai 3 capsule may inhibit the development of DF.
出处
《中国中西医结合外科杂志》
CAS
2006年第6期521-524,共4页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
基金
黑龙江中医管理局资助项目(HZ2001-022)
