摘要
目的 观察甲泼尼龙冲击治疗小儿麻疹并重症肺炎的临床疗效。方法 将42并重症肺炎患儿随机分成观察组22例和对照组20例。观察组除接受一般治疗外.采用甲泼尼治疗,初20~30mg/(kg·d)。每12小时一次,治疗3d,后减为5~10mg/(kg·d)。治疗2~3d,改米松0.2~0.3mg/(kg·d),维持2~4d。结果 观察组患儿在呼吸困难、肺部啰音、血气、胸片恢上均较对照组短,差异有统计学意义,且机械通气病例明显减少(P〈0.05)。结论 甲泼尼龙冲麻疹并重症肺炎患儿有效。
Objective To evaluate the efficacy of pulse methylprednisolone therapy (PMT) on severe measles pneumonia in children. Methods Forty-two children with severe measles pneumonia were randomly divided into two groups: PMT group(22 cases) and control group(20 cases). Both groups were treated by clinical routine therapy, furthermore, twenty-two patients of PMT group received 20-30 mg/(kg·d) methylprednisolone intravenously every 12 hours for 3 days, and then 5- 10 mg/( kg·d) intravenous methylprednisolone for 2 - 3 days followed by Dexamethasone 0.2 - 0.3 mg/( kg·d) for 2- 4 days. Results In contrast to the control, PMT group had significantly shorter recovery time of dyspnea, rales, hypoxia and chest x-ray abnormality. PMT group had a lower incidence of mechanical ventilation than the control group (P 〈 0.05 ). Conclusion Pulse methylprednisolone therapy is effective on severe measles pneumonia in children.
出处
《中国小儿急救医学》
CAS
2006年第6期520-521,共2页
Chinese Pediatric Emergency Medicine
关键词
甲泼尼龙
麻疹
重症肺炎
儿童
Methylprednisolone
Measles
Severe pneumonia
Infant