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多巴胺D3受体选择性配体研究进展 被引量：2

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摘要 多巴胺D3受体(D3R)主要集中分布在与认知、情感、行为动机密切相关的中脑边缘,预示了以D3R为靶标治疗帕金森病、精神分裂症、药物成瘾等中枢疾病具有潜在的价值。为进一步揭示D3R与中枢病变的联系,高选择性D3R配体的优化成为研究热点,本文综述了以D3R为靶标治疗中枢疾病的潜在价值及D3R选择性配体的构效关系研究进展。
作者 祝辉 杨日芳 李锦 姜玉 恽榴红
机构地区 中国人民解放军军事医学科学院毒物药物研究所 中国人民解放军成都军区联勤部药品仪器检验所
出处 《解放军药学学报》 CAS 2006年第6期441-445,共5页 Pharmaceutical Journal of Chinese People's Liberation Army
基金 国家973计划资助项目 No.2003CB515400
关键词 多巴胺D3受体 构效关系
分类号 R914 [医药卫生—药物化学]
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参考文献41

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共引文献20

同被引文献21

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二级引证文献16

解放军药学学报
2006年 第6期

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