期刊文献+

子宫颈癌与DNA倍体及S期细胞比率的关系和临床意义 被引量:2

Relationship between cervical cancer and DNA ploid and S period cellular ratio and its clinical significance
下载PDF
导出
摘要 目的:探讨宫颈癌DNA含量和宫颈癌早期诊断的关系。方法:应用流式细胞仪检测正常宫颈、宫颈炎、C IN、宫颈癌组织和脱落细胞DNA含量。结果:正常宫颈S期和G2期细胞比例没有明显升高,没有发现DNA异倍体。宫颈癌组织中DNA异倍体含量和G2期细胞较其它组织明显增高,组织和脱落细胞结果无明显不同。结论:DNA异倍体有助于宫颈癌的早期诊断。 Objective: To investigate the relationship between the content of DNA in cervical cancer tissues and the earlier diagnosis of cervical cancer. Methods: The content of DNA in tissues and exfoliated cells of normal cervix, cervicitis, CIN and cervical cancer were analyzed by flow cytometer (FCM). Results: The percentage of S stage and G2 stage ceils in tissues of normal cervix were not apparently increased and DNA beteroploid was not found; the content of DNA heteroploid and G2 stage cells were apparently higher in tissues of cervical cancer than that in other tissues (P 〈 0.05). Conclusion: DNA beteroploid is helpful in the early diagnosis of cervical cancer.
出处 《中国妇幼保健》 CAS 北大核心 2006年第24期3426-3428,共3页 Maternal and Child Health Care of China
关键词 子宫颈癌 DNA倍体 SPF 流式细胞仪 Cervical cancer DNA ploid SPF Flow cytometer (FCM)
  • 相关文献

参考文献4

  • 1Yang L, Parkin DM, Li LD et al. Estimation and projection of the nation profile of cancer mortality in China : 1991 - 2005. Br J Cancer,2004, 90:2157-2166
  • 2Stenkvist B, Soderstorm J. Reasons for cervical cancer despite extensive screening. J Med Screen, 1996, 3 (4) : 204-207
  • 3Hutchinson M, Fertitta L, Goldbaum B et al. Cervex - Brush and cytobrush comparison of their ability to sample abnormal cells for cervical smers. J repord Med, 1991, 36 (8) : 581 -586
  • 4张秋实,其木格,李继俊.子宫内膜癌39例p16蛋白细胞周期素D_1DNA倍体及S期细胞比率的检测及其临床意义[J].中国实用妇科与产科杂志,2002,18(12):741-742. 被引量:2

二级参考文献5

  • 1Wang YF,Chung KH,Chung TH,et al.p16INK4 and p15INK4d alteration in primary gynecologic malignancy[].Gynecologic Oncology.1997
  • 2Schmitz MJ,Hendrieks DT,Farley J,et al.P27 and cyclin D1 abnormalities in uterine serous carcinomas[].Gynecologic Oncology.2000
  • 3Shimizu M,Saitch Y,Itoh H.Immunohistochemical staining of H-ras oncogenic product, benign and malignant human pancreatic tissues[].Human Pathology.1990
  • 4Friberg LG,Noren H,Deiie U.Prognostic value of DNA ploid and phase fraction in endometrial cancer stage Ⅰand Ⅱ: a prospective 5-year survival study[].Gynecologic Oncology.1994
  • 5Pfister J,Kommoss F,Sauerbrei W,et al.Prognostic value of DNA ploid and S-phase fraction in stage I endometrial carcinoma[].Gynecologic Oncology.1995

共引文献1

同被引文献23

引证文献2

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部