摘要
目的:调查黄疸婴儿人类巨细胞病毒感染的情况。方法:采用荧光定量PCR方法对203例黄疸婴儿尿液标本进行HCMV-DNA定量检测。结果:在所检测的203例婴儿中,HCMV-DNA阳性的有52例,感染率为25.62%。HCMV-DNA拷贝数与黄疸持续时间无相关性。结论:HCMV是引起婴儿黄疸的主要原因之一,荧光定量PCR检测婴儿尿液中的HCMV-DNA快速、方便,检出率高,可及时诊断出巨细胞病毒的感染,以便及时治疗,降低畸形儿发生率。
Objective: To investigate the status of human cytomegalovirus (HCMV) infection in infants with jaundice. Methods: FQ - PCR was used to detect HCMV - DNA in urine from 203 infants with jaundice. Results: Among the 203 cases, 52 were positive (25.62%). The level of HCMV - DNA was not correlated with clinically apparent disease. Conclusion: HCMV is one of the factors resulting in infants with jaundice. FQ - PCR assay can monitor HCMV infection of infants with jaundice to treat them and decrease birth rate of abnormal infant effectively.
出处
《中国妇幼保健》
CAS
北大核心
2006年第24期3430-3431,共2页
Maternal and Child Health Care of China
关键词
人类巨细胞病毒
黄疸CMV-DNA
荧光定量PCR
Human cytomegalovirus (HCMV)
Jaundice
CMV - DNA
Fluorescent quantitative PCR (FQ - PCR)