大豆皂甙饮料缓解体力疲劳作用的实验研究

Study on the Alleviative Effect of Beverage Containing Soy Saponins on Physical Fatigue

目的:研究大豆皂甙饮料的缓解体力疲劳作用。方法:采用雄性ICR小鼠,大豆皂甙饮料按33.3ml/kg.bw、66.7ml/kg.bw、100.0ml/kg.bw连续灌胃30d,测定小鼠负重游泳时间、血乳酸、血清尿素氮和肝糖原含量。结果:100.0ml/kg.bw剂量组小鼠负重游泳时间显著长于对照组(P<0.05).66.Tml/kg.bw剂量组游泳后0min血乳酸含量和3个时点血乳酸曲线下面积显著低于对照组(P<0.05、P<0.01)。33.3ml/kg.bw剂量组肝糖原含量显著高于对照组(P<O.05)。结论:大豆皂甙饮料具有缓解体力疲劳的作用。

Objective： The alleviative effect of beverage containing soy saponins on physical fatigue was studied. Method： Male ICR mice were divided into four groups： distilled water control and three experimental groups in which the doses of beverage containing soy saponins were 33.3, 66.7 and 100 ml/kg.bw respectively. After orally administered for 30 days, loaded swimming time, blood lactic acid, serum urea nitrogen and glycogen in liver were determined. Results： The loaded swimming times of mice in the group of 100 ml/kg.bw was significantly longer than that in the group of distilled water control （P〈0.05） . The blood lactic acid level 0 minute after swimming and the area under the blood lactic acid curve of before, 0 minute and 20 minutes alter swimming in the group of 66.7ml/kg.bw were significantly smaller than those in the groups of distilled water control （P〈0.05,P〈0.01） . The content of Liver glycogen in the group of 33.3ml/kg.bw was significantly more than that in the group of distilled water control （P〈0.05） . Conclusion： The beverage containing soy saponins can alleviate physical fatigue in mice.