中药皂苷类成分防治糖尿病的药理研究进展

Pharmacological Progress on prohibiting and treating diabetes with saponin compounds in Chinese medicine

中药皂苷是一类高药理活性的天然化合物,通过降血糖、调血脂、改善胰岛素水平和糖耐量等途径能够起到有效防治糖尿病的作用。近年关于中药皂苷类成分防治糖尿病的药理研究表明,进一步从天然药物中筛选皂苷类成分,研究开发防治糖尿病及其并发症的先导化合物或中药制剂,具有重要的理论意义与应用价值。

Saponins in Chinese medicines are a kind of natural compounds with high pharmacological activities,which can prohibit and relieve diabetes by decreasing the level of blood sugar,adjusting blood fat and improving the level of insulin and the tolerance to sugar.Recent pharmacological researches demonstrated that it would have theoretical significance and practical value to further screen saponins from natural herbs and develop pilot compounds or pharmaceutics of Chinese medicine for preventing and treating diabetes.