兔脑和脊髓内开胃素A免疫阳性神经元和神经纤维的分布

Distribution of Orexin A-like immunoreactive neurons and nervous fibers in the brain and spinal cord of rabbit

采用免疫组织化学法研究了10只青紫蓝兔脑内开胃素(O rexin)A免疫阳性神经元和神经纤维的分布。结果显示,O rexin A免疫阳性神经元分布于下丘脑的视上核、室旁核、背内侧核、穹隆周核、外侧区、前区和后区以及底丘脑的未定带。O rexin A免疫阳性神经纤维广泛分布于中枢神经系统内,在端脑分布于大脑皮质、尾状核、隔核和杏仁核;在间脑分布于丘脑、下丘脑、上丘脑和垂体;在中脑分布于中央灰质、前丘、后丘、黑质、网状结构和中缝核;在脑桥分布于蓝斑、网状结构和中缝核;在延髓分布于极后区、孤束核和迷走神经背侧运动核;在小脑和脊髓也有分布。

Distribution of Orexin A-like immunoreactive （OXA-IR） neurons and nervous fibers in the brain and spinal cord of rabbit was studied by immunohistochemistry. The results were as follows： OXA-IR neurons were observed in the paraventricular and dorsomedial hypothalamic nuclei, supraoptic nucleus, perifornical nucleus, the anterior, lateral and posterior hypothalamic area, and the zona incerta of the subthalamus. OXA-IR nervous fibers were observed in the central nervous system widely. In the telencephalon, OXA-IR nervous fibers were present in the cerebral cortex, caudate nucleus, amygdala nucleus and septal area. In the diencephalon, OXA-IR nervous fibers were observed in the thalamus, hypothalamus, epithalamus and hypophysis. In the mesencephelon, OXA-IR nervous fibers were located in the central gray substance, superior and inferior colliculi, substantia nigra, reticular formation and raphe nuclei. In the pons, OXA-IR nervous fibers were seen in the locus coeruleus, reticular formation and raphe nuclei. In the medulla oblongata, OXA-IR nervous fibers were found in the area postrema, solitary tract nucleus and dorsal motor nucleus of the vagus nerve. OXA-IR nervous fibers were also present in the cerebellum and spinal cord.