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反向遗传学技术对呼吸道病毒研究的促进作用

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摘要 反向遗传学技术,即病毒的全长感染性cDNA克隆技术,它解决了对RNA病毒基因组难以操作这一多年难题。由于多数呼吸道病毒属于RNA病毒,因此反向遗传学技术在深入研究呼吸道病毒基因组结构功能、研制筛选候选疫苗株等方面显示出非常好的应用前景。本文就呼吸道病毒反向遗传学技术的建立及应用进展进行了综述。
作者 李兵 陈杭薇
出处 《国际呼吸杂志》 2006年第12期905-907,共3页 International Journal of Respiration
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