摘要
中国医科大学碘致甲状腺疾病课题组首次完成了不同碘摄入量社区甲状腺疾病发病率的五年前瞻性流行病学研究。研究结果显示,碘超足量和碘过量可以导致自身免疫甲状腺炎和亚临床甲状腺功能减退症(甲减)的发病率显著增加;可以促进甲状腺自身抗体阳性的人群发展为甲减。碘超足量和碘过量主要影响甲状腺疾病易感人群。所以,应该倡导科学补碘,实行区域化、个体化的补碘方针。
For the first time, the iodine-induced thyroid diseases group of China Medical University has finished a five-year prospective epidemiological study on the incidences of thyroid diseases in the three communities with various levels of iodine intake. The results indicated that increased incidences of subclinical hypothyroidism and autoimmune thyroiditis in the communities with more than adequate and excessive iodine intake. The individuals with positive thyroid autoantibodies at baseline more likely became hypothyroid due to more than adequate and excessive iodine intake. These adverse effects are mainly involved in the susceptible populations for thyroid diseases. Hence it appears to be reasonable that iodine supplementation should be conducted by localization and individualization.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2006年第6期510-511,共2页
Chinese Journal of Endocrinology and Metabolism