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肥胖患者大网膜脂肪脂联素mRNA表达及相关因素的研究 被引量:2

Expression of adiponectin mRNA and related factors in greater omentum fat tissue in obese subjects
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摘要 选择43例择期外科手术患者,用RT-PCR法检测大网膜脂肪组织脂联素表达水平。发现肥胖患者的大网膜脂肪组织中脂联素表达明显降低,腹型肥胖、胰岛素抵抗以及肿瘤坏死因子-α是大网膜脂肪组织脂联素表达水平的主要影响因素。 The expression of adiponeetin mRNA in greater omentum fat tissue was measured in 43 subjects using RT-PCR. The results showed that the expression of adiponeetin mRNA in greater omentum fat tissue was signitieantly lower in obese subjects than that in normal persons, and abdominal obesity, HOMA-IR and tumor necrosis factor-α were the main independent factors influencing the expression of adiponeetin mRNA in greater omentum.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2006年第6期562-563,共2页 Chinese Journal of Endocrinology and Metabolism
基金 安徽省自然科学基金资助项目(03043719) 安徽省卫生厅基金资助项目(2002A008)
关键词 脂联素 肥胖症 胰岛素抵抗 逆转录聚合酶链反应 Adiponectin Obesity Insulin resistance Reverse transcriptase polymerase chain reaction
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