复方中药对亚临床肝性脑病治疗作用临床研究

A Clinical Study on Therapeutic Effect of Chinese Traditional Compound Medicine on Subclinical Hepatic Encephalopathy

目的观察复方中药对亚临床肝性脑病(SHE)的治疗作用。方法将52例肝硬化伴亚临床肝性脑病病例随机分为治疗组和对照组,对照组接受常规护肝治疗,治疗组在常规治疗的基础上,加用复方中药水煎剂。2周为1疗程,观察患者的数字连接试验(NCT)、脑电图(EEG)、肝功能、血氨等的改善情况。结果治疗组的NCT时间、脑电图以及肝功能血氨等生化指标较对照组改善,两组比较,有显著性差异(P<0·01)。结论由虎杖、生山楂、酸枣仁、蒲公英、石菖蒲等组成的复方中药对亚临床肝性脑病患者有显著疗效。

Objective To observe the therapeutic effects of Chinese traditional compound medicine on subcilincal hepatic encephalopathy（SHE）. Methods 52 patients with liver cirrhosis complicated by SHE were randomly divided into treatment group and control group. The patients of control group received conventional hepatopretection treatment, and the patients of treatment group were given conventional treatment and Chinese traditional compound medicines. Number connection test（ NCT）, electroencephalogram （EEG）, liver function, blood ammonia were investigated after 2 weeks of treatment. Resuhs The number connection test （ NCT）, electroencephalogram （EEG） ,liver function,blood ammonia were significantly improved in the treatment group than that in the control group（ P 〈 0.01 ）. Conclusion The effects of the Chinese traditional compound medicines （ compose of Polygonum cuspidatum, raw hawthornfruit, seed of Zizyphus jujuba Mill, Mongolian Dandelion Herb and Rhizoma Acoori Graminei ） in SHE treatment is significant.