部分脾动脉栓塞术治疗肝硬化门脉高压症46例

Partial spleen artery embolotherapy for 46 patients with hepatic cirrhosis and portal hypertension

目的:探讨部分脾动脉栓塞术(PSE)治疗肝炎肝硬化门静脉高压症并发脾功能亢进的疗效及临床意义.方法:通过我院46例肝炎肝硬化门静脉高压症并发脾功能亢进患者行PSE,观察术前及术后血象变化、脾脏大小变化、门静脉内径变化及并发症情况.结果:与术前相比,术后白细胞及血小板计数明显上升,3mo后稳定在一定水平,红细胞计数术前及术后无明显变化,脾脏3mo后明显缩小,门静脉内径不同程度缩小,术后无严重并发症发生.结论:PSE治疗肝炎肝硬化门静脉高压症合并脾功能亢进安全有效.

AIM： To study the curative effect and clinical significance of the partial spleen artery embolization （PSE） in the treatment of hepatic cirrhosis together with portal hypertension and hypersplenism. METHODS： Forty-six patients with hepatic cirrhosis accompanied by hypersplenism and portal hypertension received PSE therapy. The variations of hemogram, spleen size, portal vein width, and the complications were observed. RESULTS： The numbers of white blood cells and thrombocytes rose a lot after the treatment and kept on a certain level after 3 months; the red blood cells had no clear variation after the treatment; spleen became much smaller after 3 months; portal vein width reduced to some extent, and no serious complications happened after the treatment. CONCLUSION： PSE is safe and effective for curing cirrhosis together with hypersplenism and portal hypertension.