期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

磷脂酰肌醇3激酶p55γ调节亚单位对胃癌细胞系MGC803细胞迁移的影响 被引量：3

原文传递
导出
作者 孙晓杰 赵玫 袁兴华 余权 黄常志
机构地区 齐齐哈尔医学院生化教研室 中国医学科学院肿瘤医院肿瘤研究所
出处 《中华医学杂志》 CAS CSCD 北大核心 2006年第46期3269-3271,共3页 National Medical Journal of China
基金 国家自然科学基金资助项目(30570904) 黑龙江省教育厅科学技术研究项目(11513115)
关键词 磷脂酰肌醇3激酶 MGC803 催化亚单位 细胞迁移 胃癌细胞系 P55 PI3K信号通路 调节
分类号 R735.2 [医药卫生—肿瘤]
  • 相关文献

参考文献13

  • 1Katso D,Okkenhaug K,Ahmadi K,et al.Cellular function of phosphoinositide 3-kinases:implications for development,immunity,homeostasis,and cancer.Annu Rev Cell Dev Biol,2001,17:615-675.
  • 2Arboleda MJ,Lyons JF,Kabbinavar FF,et al.Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins,increased invasion,and metastasis of human breast and ovarian cancer cells.Cancer Res,2003,63:196-206.
  • 3Grille SJ,Bellacosa A,Upson J,et al.The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.Cancer Res,2003,63:2172-2178.
  • 4Agarwal A,Das K,Lerner N,et al.The AKT/I kappa B kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-kappa B and beta-catenin.Oncogene,2005,24:1021-1031.
  • 5Xia X,Serrero G.Multiple forms of p55PIK,a regulatory subunit of phosphoinositide 3-kinase,are generated by alternative initiation of translation.Biochem J,1999,341:831-837.
  • 6Trifonova R,Small D,Kacer D,et al.The non-transmembrane form of deltal,but not of jagged1,induces normal migtatory behavior accompanied by fibroblast growth factor receptor 1-dependent transformation.J Biol Chem,2004,279:13285-13288.
  • 7Doehl D,Hoeflich A,Wolf E,et al.Insulin-like growth factor (IGF)-binding protein-4 inhibits colony formation of colorectal cancer cells by IGF-independent mechenisms.Cancer Res,2004,64:1600-1603.
  • 8Fridman R,Fuerst TR,Bird RE,et al.Domain structure of human 72-kDa gelatinase/type Ⅳ collagenase.Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions.J Biol Chem,1992,267:15398-15405.
  • 9Lauffenburger DA,Horwitz AF.Cell migration:a physically integrated molecular process.Cell,1996,84:359-369.
  • 10Woodhouse EC,Chuaqui RF,Liotta LA.General mechanisms of metastasis.Cancer,1997,80:1529-1537.

同被引文献43

  • 1孙晓杰,赵玫,袁兴华,余权,郑利民,方明镜,黄常志.PI3K p55PIK调节亚单位N末端抑制胃癌细胞株MGC803生长及其机制[J].癌症,2006,25(3):264-268. 被引量：2
  • 2Katso R, Okkenhaug K, Ahmadi K, et al. Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. Annu Rev Cell Dev Biol, 2001, 17:615.
  • 3Leslie NR, Yang X, Downes CP, et al. The regulation of cell migration by PTEN. Biochem Soc Trans, 2005, 33(Pt 6): 1507.
  • 4Wymann MP, Zvelebil M, Laffargue M. Phosphoinositide 3-kinases singnaling-which way to target? Trends Pharmacol Sci, 2003, 24 (7) : 366.
  • 5Zheng H, Fu G, Dai T, et al. Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal transduetion pathway. J Cardiovasc Pharmacol, 2007, 50(3) : 274.
  • 6Mareel M, Leroy A. Clinical, cellular, and molecular aspects of cancer invasion. Physiol Rev, 2003, 83(2): 337.
  • 7Wu MH, Hong TM, Cheng HW, et al. Galectin-1-mediated tumor invasion and metastasis, up-regulated matrix metalloproteinase expression, and reorganized aetin cytoskeletons. Mol Cancer Res, 2009, 7(3): 311.
  • 8Guo H, Gu F, Li W, et al. Reduction of protein kinase C zeta inhibits migration and invasion of human glioblastoma cells. J Neurchem, 2009, 109(1): 203.
  • 9Ridley AJ. Rho GTPases and cell migration. J Cell Sci, 2001, 114 (Pt 15): 2713.
  • 10Raftopoulou M, Hall A. Cell migration: Rho GTPases lead the way. Dev Bio, 2004, 265:23.

引证文献3

二级引证文献4

中华医学杂志
2006年 第46期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部