衍射增强成像与成像应用实验

Diffraction Enhanced Imaging and Imaging Application Experiment

目的:目前的常规X线医学成像是通过吸收衬度成像,但分辨率不够高,由于DEI采用相位衬度机制而不是依赖于物体的吸收,故适合弱吸收组织尤其是软组织成像。本实验旨在评价DEI在生物医学样品成像中的诊断价值。材料和方法:大鼠脏器样品切片,在BSRF的4W1A束线上进行DEI方法成像。首先扫描获得摇摆曲线,再选择摇摆曲线上不同位置进行成像,成像结果与常规吸收像进行对照,分辨率通过显微放大法获得。结果:图像能显示常规医学X成像方法无法显示的肝脏微细结构,分辨率达到微米。结论:DEI的优良分辨率和衬度将有望改进生物医学组织的影像诊断水平。

At present, the conventional medical X- ray imaging is imaged with absorption contrast, the resolution isn＇t enough high, however, DEI images by the phase- contrast, not the absorption imaging mechanism, which is adapt to weak- absorption tissue imaging, especially the soft issue. The experiment is aim to evaluate the imaging diagnosis value of DEI in biology medical. Materials and Methods ： Mouse viscera（including liver and kidney） sample slice are imaged in the 4W1A line of the BSRF. At first rocking curve is scanned, then different locations in the rocking curve are selected to be imaged, the imaging result is compared with conventional imaging, and the resolution is calculated by micro - magnify method. Results： The imaging can display the microstructure, which cannot be shown with the conventional medical X- ray imaging way, and the resolution reaches to micron. The different locations have influence on the imaging result. Conclusion： With the outstanding resolution and contrast, it is hopeful for the DEI to improve the imaging diagnosis level of the biology medical tissue.