摘要
目的:探讨临床型磁共振成像仪用于动物实验成像扫描参数的优化。材料和方法:利用1.5T磁共振成像仪对不同部位接种的52只兔VX2肿瘤模型进行常规自旋回波(T1WI,T2WI)及梯度回波扫描,并进行Gd-DTPA和铁剂增强扫描,比较各种序列图像质量并比较不同部位肿瘤/组织对比信噪比。结果:T2WI和增强扫描可以提供较好的肿瘤病灶的组织对比显示。结论:选择适当的成像参数可以在临床型磁共振成像仪上获得较好的动物图像。
Purpose： To evaluate the effects of different scan sequences used in animal experiment on a clinical MRI scanner. Materials and Methods： 52 rabbits with VX2 tumor in different anatomy sites were scanned in different sequences with a 1.5T MRI scanner. Gd - DTPA and SPIO were also administrated. The tissue contrast ratio between tumor and normal tissue were compared. Results： T2WI and contrast scan can well show tumors in different sites. Conclusion： Optimal selection of imaging parameter can also give high quality images on clinical 1.5T MRI in animal experiment.
出处
《中国医学计算机成像杂志》
CSCD
2006年第6期426-428,共3页
Chinese Computed Medical Imaging
基金
国家自然科学基金资助(基金编号:30170286)
