饮食与患前列腺癌危险性的关系研究

A Case-control Study on Diet and Risk of Prostate Cancer

目的探讨前列腺癌发病的饮食影响因素,为前列腺癌的科学防治提供理论依据。方法设计饮食频度问卷,对88例经组织病理学或细胞学检查确诊的前列腺癌患者及按配比要求选配的120例对照者的饮食情况进行调查;通过SPSS13．0软件对资料进行分析。结果单因素分析显示,食用蔬菜、水果、蛋类、牛奶及喝茶与患前列腺癌有统计学关联(P<0．05)。多因素逐步非条件Logistic回归分析显示,食用蛋类、牛奶与忠前列腺癌危险性增加有关(P<0．05);食用蔬菜、水果及喝茶的频度则与前列腺癌危险性降低有关联(P<0．05)。未发现喜食辛辣食物、鱼类、牛羊肉等与患前列腺癌有关。结论食用蔬菜、水果及喝茶使患前列腺癌危险性降低;蛋类、牛奶等高脂肪类食物是前列腺癌发生的危险因素。

Objective To investigating the risk factors of prostate cancer, and provide scientific basis for prevention and treatment of prostate cancer. Methods With an identical food frequency questionnaire, a survey of 88 patients with prostate cancer and 120 matched controls was conducted. The data were analyzed with SPSS 13.0 version. Results Single factor analysis showed that there is statistical relation between eating vegetables,fruits,eggs,milk,tea and prostate cancer（P〈0.05）. Multivariate stepwise unconditional Logistic regression analysis results showed that the consumption frequency of eating eggs, milk was an independent risk factor for prostate cancer（P〈0.05）.The diet frequency of eating vegetables, fruits and tea was the independent protective factor for prostate cancer（P〈0.05）.No association was found between diet frequency of eating mutton, beef, fishes, salty and pungent food and the risk of prostate cancer. Conclusion Eating vegetables, fruits and tea is the important protective factor from prostate cancer ,while eating eggs, milk is the risk factor for the cancer.