摘要
目的:评价雷帕霉索洗脱支架(Cypher^(TM))和紫杉醇涂层支架(Taxus^(TM))治疗冠心病(CAD)合并2型糖尿病(DM)患者短期疗效和安全性。方法:从2002年12月至2006年3月共116例合并CAD和DM的患者入选本研究,共植入药物涂层支架186个(雷帕霉素洗脱支架97个,紫杉醇涂层支架89个)。观察6个月的主要心血管不良事件(MACE)。结果:接受两种支架植入的患者基本临床特征相似。支架植入成功率100%,95%的患者完成了6个月的随访。雷帕霉素洗脱支架组总的MACE事件发生率约为6.78%(4/59),紫杉醇涂层支架组总的MACE事件发生率约为7.02%(4/57),两组相比无统计学差异。结论:雷帕霉素洗脱支架和紫杉醇涂层支架治疗CAD合并2型DM的患者有相似的疗效。
Objective: To compare the short-term clinical outcomes of rapamycin (sirolimus) eluting stent (CYPHER^TM) and paclitaxel eluting steut (Taxus^TM) in treatment of coronary coronary disease patients with type 2 diabetes. Methods: 116 coronary artery disease and diabetes patients with 186 lesions, were treated with 97 rapamycin eluting stents and 89 paclitaxel eluting stents. 3he short - term(6 months) outcomes were compared between these 2 groups. Results: 3he success rate of steut implantation was 100%, major adverse cardiac eveut(MACE), during 6 months followup, MACE were 6.78% and 7.02% in the rapamycin eluting stent group and paclitaxel eluting stent group, and there was no significantly difference. Conclusion: The efficacy of rapamycin eluting and paclitaxel eluting stent were similar in coronary heart disease patients with type 2 diabetes.
出处
《中国医药导刊》
2006年第6期414-416,共3页
Chinese Journal of Medicinal Guide
关键词
冠心病
糖尿病
药物洗脱支架
Coronary artery disease
Diabetes
Drug - eluting Steut