无症状体检人员C-反应蛋白及血脂与动脉粥样硬化的关系

The relation between atherosclerosis and C-reactive protein、blood lipids of healthy symptomless crowd in the physical checkup

目的:探讨无症状体检人员C-反应蛋白(CRP)及血脂与动脉粥样硬化之间的关系。方法:无症状人员186人分别测其颈总动脉内-中膜厚度(IMT)及血脂。血脂包括总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)。结果:IMT为(0.987±0.42)mm,CRP(3.98±3.79)mg/L,TC(5.89±0.99)mmol/L,TG(2.38±1.87)mmol/L,HDL-C(1.36±0.87)mmol/L,LDL-C(3.63±0.94)mmol/L。IMT与CRP无显著性相关(P>0.05),而CRP≥8.0mg/L组与IMT呈显著性正相关(P<0.05)。以CRP为因变量,血脂、血压、年龄等为自变量进行多因素逐步回归分析,CRP、TG与IMT呈显著性正相关(P<0.05)。结论:提示无症状人员CRP与TG同时增加并超出正常值上限则有动脉粥样硬化倾向,其严重程度呈正相关。

Objective：To explore the relationship between C - reative protein（ CRP） ,blood lipids of healthy symptomlees crowd in the physical checkup and atheroscleresis. Methods： 186 Healthy symptomless people in the physical checkup who were monitoring their CRP, blood lipids and neck total after fee - Chinese fill thickness. Results： IMT（ x）0.987 ± 0.421 mm, CRP （ x ）3.98 ± 3.79mg/L, TC （ x ）5.89 ± 0.99mmol/L, TG （ x ）2.38 ± 1.87 mmol/L, HDL - C （ x ） 1.36 ± 0.87mmol/L, LDL - C （ x ） 3.63 ± 0.94mmol/L. IMT and Clip no significant ditterences（ P 〉 0.05）. To CRP as result of variables to blood lipids , blood pressure, age and other factors as independent variables for more togreesion analysis. CRP, a significant streamlining of being associated with IMT（ P 〈 0.05）. Conclusion：The result showed that CRP and TG of healthy symptomless crowd at the same time increase the ceilig beyond the normal value should apply to have atherosclerosis, and the extent of its CRP,TG levels were being relevant.