摘要
为了手指再造,手的肌腱、腱鞘及骨缺损、关节毁坏等的修复,建立生物性能良好的尸手冷藏库。将健康青年外伤死亡的新鲜尸手,从腕部离断,消毒、灭菌、包装、标记后,置入深低温冰箱内保存,移植前剥除皮肤组织,再浸泡在抗生素溶液内1小时,复温。结果表明:冷冻的异体手指复合组织移植后排斥反应不明显,异体骨与宿主骨镶嵌连接,未镶嵌的部位有骨吸收、关节变性。异体肌腱与宿主肌腱连接牢固。证明,医院建立尸手冷藏库是可行的,与建立骨库具有同等意义,能为临床提供骨、关节、肌腱。
In order to supply allografts for reconstruction of finger, repair of tendon or tendon sheath, the hands from fresh cadavers of healthy young persons who died from accident were amputated at the wrist level. After disinfected, packed and labelled, the hands were stored into a deep freezer at -30℃ as bank storage. Before grafting, the skin and subcutaneous tissue were stripped from the frozen finger. Then it was immersed in an antibiotic fluid for 1 hour. The results showed that the immunological antigenicity of allograft was decreased by the freezing method. Bony union between the impacted host bone and the allogeneic phalangeal bone was seen on X ray films. Bone absorption and joint degeneration were found at the area where no impaction between bones. The healing between tendons from host and that from the allografts was strong. It was concluded that establishing a cadaveric hand bank in hospital was as important as establishing a bone bank for the supply of bone, joint, tendon, tendon sheath and finger composite tissue, for allogeneic grafts.
出处
《中国修复重建外科杂志》
CAS
CSCD
1996年第3期152-154,共3页
Chinese Journal of Reparative and Reconstructive Surgery