小儿重症肺炎血中自由基变化及临床意义

Changes in Blood Free Radical Level in Infant Severe Pneumonia and Its Clinical Significance

通过测定３６例重症肺炎患儿极期及２０例健康小儿血中ＬＰＯ含量及ＳＯＤ活性，证实重症肺炎患儿血中自由基水平明显升高，清除自由基能力明显下降；且随器官衰竭数目增多，上述变化更显著。提示血ＬＰＯ含量及ＳＯＤ活性可判断小儿重症肺炎的严重程度及预后，治疗小儿重症肺炎时可加用自由基清除剂。

singnificant elevation of serum LPO concentration and a marked reduction of erythrocyte Cu Zn-SOD activity were o bserved in 36 cases of infant severe pneumonia in contrast with 20 cases of normalchildren. The result indicated t hat the blood free radical level was higher and the ability of scavengingfree radical was lower in the patient,ds well as that blood LPO concentration and CuZn-SOD activitycoala be used to assess the severity and its prognosis of the disease.It was also offered that free radical could be used to treat infant severe pneumonia.