摘要
通过测定36例重症肺炎患儿极期及20例健康小儿血中LPO含量及SOD活性,证实重症肺炎患儿血中自由基水平明显升高,清除自由基能力明显下降;且随器官衰竭数目增多,上述变化更显著。提示血LPO含量及SOD活性可判断小儿重症肺炎的严重程度及预后,治疗小儿重症肺炎时可加用自由基清除剂。
singnificant elevation of serum LPO concentration and a marked reduction of erythrocyte Cu Zn-SOD activity were o bserved in 36 cases of infant severe pneumonia in contrast with 20 cases of normalchildren. The result indicated t hat the blood free radical level was higher and the ability of scavengingfree radical was lower in the patient,ds well as that blood LPO concentration and CuZn-SOD activitycoala be used to assess the severity and its prognosis of the disease.It was also offered that free radical could be used to treat infant severe pneumonia.
出处
《中国医科大学学报》
CAS
CSCD
1996年第4期397-398,共2页
Journal of China Medical University
关键词
肺炎
过氧化脂质
超氧化物歧化酶
儿童
infant severe pneumonia
lipid peroxide
s uperoxide dismutase