异舒吉治疗不稳定型心绞痛90例疗效观察

Curative Observation on Treatment of Unstable Angina with Isosorbide Dinitrate

目的 总结临床应用异舒吉（二硝酸异山梨酯）静脉制剂和对照组应用硝酸甘油静滴治疗90例不稳定型心绞痛。方法 A组用异舒吉40mg加入生理盐水500mL，1次／d静点；B组用硝酸甘油20mg加入生理盐水500mL，7-8滴／min，1次／d静点，两组连续观察1周。结果 异舒吉治疗不稳定型心绞痛在减少心绞痛发作次数、心率、血压、静息心电图变化、不良反应发生率等方面，优于硝酸甘油。结论 异舒吉临床疗效确切，副作用小，使用方便。

Objective To summarize the curative effect of unstable angina treated with isosorbide dinitrate compared with nitroglycerin. Methods The group A was treated with ID 40 mg/d i. v and group B was treated with nitroglycerin 20mg per day for a week. Results There was much better in episode time, HR, Bp, ECG and side effect in group A than those in group B. Conclusion The ID might have good curative effect with less side effect and easy use.