2004-2006年吉林省流行性感冒病原学变化特点

Virological Characteristic of Influenza in Jilin Province

目的探讨吉林省流行性感冒的病原学变化特点。方法根据2004-2006年流感监测结果对吉林省流感的流行趋势、病原学变化特点进行综合分析。用细胞培养法分离并鉴定流感病毒,用微量半加敏血凝抑制试验方法检测人群中抗流感病毒抗体水平。结果监测哨点医院2004-2006年临床诊断的流感样病例数基本持平,冬季可见1个波峰;全省发生暴发疫情0起;两个监测年从1 350标本中分离病毒71株,其中甲1型39株(54.93%),甲3型7株(9.86%),乙型(yamagata株系)流感病毒24株(33.80%),乙型(victorian株系)流感病毒1株(1.41%),;正常人群抗体水平测定以抗A3抗体最高,抗乙型(victorian株系)抗体最低。结论2004-2006年吉林省流感流行以低水平散发为主。提示在今后的监测工作中除了及时发现甲型变异株的出现,还应密切关注乙型(victorian株系)的流行动态。

Objective To study influenza epidemic tendency in jilin. Methods The influenza epidemic tendency and the etiological characteristic were analyzed by the result of surveillance in 2004 - 2006. MDCK was to isolate the influenza viruses from samples, and human antibodies against influenza viruses were detected by using the Heamlogical inhibitor . Results ILl was like in tow years,there were one peak in winter,71 isolates of influenza virus were isolated from I 350 clinic samples,Al type were 39 （54.93%） ,A3 virus were 7（9.86% ）,B type （Yamagata-like） virus were 24（33.80% ） ,B type （victorian -like） virus were 1 （1.41% ）. The antibody of influenza A3 was MAX, The antibody of type B （victorian - like）was MIN. Conclusion Influenza in vogue is by lower level to spread in Jilin province 2004 - 2006. Besides finding out the variation substance of first - model in time, We should pay attention to prevalent developments of second- model（victorian- like）.